Midway Stakeholder Symposium
1st November 2023| Organized by the University of Copenhagen and EMBL-EBI Hinxton| #MSS2023
1st November 2023| Organized by the University of Copenhagen and EMBL-EBI Hinxton| #MSS2023
Over the past two decades, human microbiome research has undergone rapid growth. Advances in metagenomics, transcriptomics and other molecular techniques help in understanding interactions between the hosts' biological processes and their microbiota. It is crucial that we better understand microbiota communities whose biological activity directly impact health and human susceptibility to disease, and can facilitate the development of innovative solutions across food, feed and health products.
Pillar 1: explores current approaches that can help us better understand these symbiotic relationships, identifies theoretical and methodological challenges, and proposes directions for future research in the field.
Many industries, government and research organizations have spent large sums funding research of human microbiome as causes of, or possible therapeutic solutions to various diseases.
Advances in genome mapping and sequencing, technologies, computational methods, biological insight and clinical applications help researchers integrate genomics into biomedical research and medical practice.
Pillar 2: examines the scope, scale and pace of cutting-edge genomic advances in health, health products and disease treatment; future research priorities and opportunities for human genomics in clinical care.
Food systems evolve to meet societal changes. Large microbiome research funding over the last decade, has increased national and global projects, including microbiomes use to improve food production and animal welfare.
Combining accepted crop science approaches (e.g metabolomics) with a new generation of omics (e.g genomics) strengthen innovation that can profile the makeup of commercial crops; understand the implications of foods in humans, on a molecular level, and more.
Pillar 3: provides a look at penetration and future direction of multi-omics in food systems and agriculture, spanning the implementation of microbial solutions in food systems, use of microbial additives in bio-based industries, to predictors for crop yield, and sustainable and ethical food production parameters.
Multi-omics approaches are creating a 'tsunami' of large data that can be utilized to understand the biology of phenotypes. This requires however, the development of new methods to integrate omics data into suitable statistical and mathematical frameworks that can illustrate functional mechanisms behind crucial genotype-phenotype associations.
Pillar 4: explores the current state of mechanistic models linking metagenomic variation to phenotypic
variation; highlights reliable resources to generate big data sets of metagenomic sequencing; applies state-of-the-art metagenomicist computational toolboxes to multi-omics analyses, FAIR research and best practice.
Department of Comparative Biomedicine and Nutrition, University of Padova, Italy
Department of Veterinary Medicine, University of Cambridge
Faculty of Biosciences, Norwegian University of Life Sciences,
Norway
Eagle Genomics | Microbiome Data Science Platform,
United Kingdom
+45 4040 3096
Marie Sorivelle
Project Manager
This project has received funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement No 952914.